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What We Research - Scientific Infrastructures and Platforms

The scientific infrastructures and platforms of the U.Porto ecosystem provide the entire community with state-of-the-art equipment and highly qualified professionals that support and promote excellence in R&D activities.

There are several scientific infrastructures and platforms scattered throughout U.Porto’s R&D ecosystem, with highly specialised technical staff and state-of-the-art equipment and infrastructures that support and foster the highest standards of quality in the University’s various activities and R&D fields.

The research ecosystem of the University of Porto participates in 24 of the 56 infrastructures recognised nationally, which make up the Portuguese Roadmap for Research Infrastructures (RNIE). Some of these infrastructures are also part of the European Roadmap for Research Infrastructures.

Scientific platforms available under the EUGLOH Alliance (Excellence Core Facilities) enable researchers from partner universities to share access to platforms and equipment.

Although mainly dedicated to serving the R&D community at U.Porto, these platforms are also open to the external community, including the industrial sector, health services or companies, who can enjoy the various services offered by the platforms. Among these services are physical-chemical analysis and chemical screening, pre-clinical and clinical research, cellular and in vivo imaging, instruments for collecting and analysing oceanographic data, physical analysis of materials by microscopy or spectrometry, among several other services.

Identified within the EUGLOH Alliance, these scientific platforms form part of the EUGLOHRIA Excellence Core Facilities: a network that allows researchers from the EUGLOH Alliance universities to access partners' platforms and equipment.

U.Porto Scientific Platforms
Genealogy Database

Description: Specialisation in the Humanities, namely in the study of Migrations, Population History, Health History, Climate Change, Maritime History, Fisheries, Traditional Farming and Cultural Heritage.

Keywords: Migrations, population history, health history, climate change, maritime history

Equipment: Computers; internet access.

Location: U.Porto Faculty of Arts and Humanities (FLUP) / CITCEM

Contact information: Maria Amorim - [email protected] - (+351) 22 607 7177

Associate Laboratory of Separation and Reaction Engineering / Catalysis and Materials

Description: Specialised in the environmental sciences, chemistry and bioproduction, and resulting from a partnership between LSRE - Laboratory of Separation and Reaction Engineering and LCM - Laboratory of Catalysis and Materials, the associate laboratory aims to promote the advancement of scientific and technological expertise in the fields of Chemical Engineering of Separation and Reaction Processes, Product Engineering, Catalysis and Carboniferous Materials, Thermodynamics and Environmental Engineering.

Keywords: Adsorption pressure variation, mobile bed simulation, parametric pumping, natural gas, biogas

Equipment: Rubotherm Microbalance, Batch Reactor, GC, HPLC, SC-HPLC, fixed bed units, PSA units, ESA unit, gas phase SMB, liquid phase SMB

Location: U.Porto Faculty of Engineering (FEUP) / LSRE-LCM

Contact information: Madalena Dias - [email protected] - (+351) 22 041 3601


European Multidisciplinary Seafloor Observatory – Portugal (EMSO-PT)

Description: Expertise in the environmental sciences, in particular ocean science and seafloor observations. EMSO-PT is a large-scale European Research Infrastructure, composed of multidisciplinary underwater observatories and other supporting infrastructures for data processing. Its objective is to provide continuous scientific information about marine environmental processes related to the interaction between the geosphere, the biosphere and the hydrosphere.

Keywords: Seafloor observations, ocean surface, underwater gliders, oceanographic data

Equipment: Generic EMSO instrument module for integration and generic use in Turtle underwater relocatable node, underwater glider network for oceanographic data collection

Location: INESC TEC

Contact information: Aníbal Matos - [email protected] - (+351) 22 508 3221

Hemodynamics Lab

Description: Expertise in the fields of infection, cardiovascular sciences and physicochemical analysis.

Keywords: Coronary artery disease (CAD) prevention, CAD prediction, CAD progression analysis, computational fluid dynamics (CFD)

Equipment: Fully equipped workstation with CFD and FSI software and licences; PIV laser (Litron Lasers, LDY-300PIV); CMOS high-speed camera (Photron FASTCAM Mini UX100); Tensiometer (Biolin, Sigma 701); High-speed PIV camera (Dantec, Speedsense M); Extensive rheometer (Thermo Scientific™ HAAKE™ CaBER™); Rotational rheometer (Diener, Zepto B); Microscopes (Leica DMIL LED, Leica DMI 5000 M, Olympus IX83).

Location: U.Porto Faculty of Engineering (FEUP) / CEFT

Contact information: João Moreira de Campos - [email protected] - (+351) 22 041 3633

Industry and Innovation Lab (iiLab)

Description: The iiLAB has expertise in the industry, innovation, production technologies, robotics, automation and smart manufacturing, with the aim of disseminating the latest advancements in advanced production technologies through the demonstration of research results, experimentation and advanced training.

Keywords: Industry, innovation, production technologies, robotics, automation

Equipment: Cargo transporter for internal logistics, outdoor cargo transport, autonomous forklift, collaborative and adaptive manipulators, collaborative robotic line for packaging

Location: INESC TEC

Contact information: António Paulo Moreira - [email protected] - (+351) 22 041 3317

INESC TEC Institutional & Research Data Repository

Description: Specialising in the area of Open Data, datasets and document repositories, INESC TEC's Institutional and Research Data Repository provides access to two data collections – the Document Repository and a Multimedia Repository. The Document Repository is composed of a wide variety of documents, organised in Communities and Collections. Communities correspond to INESC TEC's organisational entities and Collections comprise the outputs of each community organised by the type of document. The Multimedia Repository contains all multimedia files produced by INESC TEC, ensuring open and free access to photographs and videos, whenever authorised by the authors.

Keywords: Document repository, open data, datasets

Equipment: DSpace Platform; CKAN Platform

Location: INESC TEC

Contact information: Soraia Ramos - [email protected] - (+351) 22 209 4091

Laboratory for Process Engineering, Environment, Biotechnology and Energy

Description: With expertise in biotechnology, nanoscience, environmental science, chemistry and bioproduction, it connects several laboratories with expertise in the fields (Energy LAB, Adsorption and Membrane Gas Separation LAB, Graphene-based biomaterials LAB, Biofilm Eng LAB, FISH LAB, Nanotechnologies LAB, Crystallisation LAB, AIR Quality and Health LAB, TRACES LAB, Multifunctional reactors Lab).

Keywords: PSC&DSC solar cells, (photo) electrochemical water separation, CO2 electro-reduction, methane decomposition, fuel cells

Equipment: Atomic layer deposition; Sputtering (up to 30 cm2); Laser glass sealing technology; Inkjet printer; Ultrasonic spray pyrolysis; IPCE; Benchtop SEM; 10 electrochemical workstations; Test bench for all electrochemical processes; BET; Microbalance (200 bar and 200 ºC)

Location: U.Porto Faculty of Engineering (FEUP) / LEPABE

Contact information: Arminda Alves - [email protected] - (+351) 22 041 3633

Machine Learning for Clinical Diagnosis / HEAL_ICT-OCNL OptIcal control and non-linear control for clinical decision support systems

Description: Specialisation in informatics.

Keywords: Machine learning, optimised control, non-linear control

Equipment: Computational Infrastructure

Location: U.Porto Faculty of Engineering (FEUP) / SYSTEC

Contact information: Fernando Pereira - [email protected] - (+351) 22 508 1857

Modular Platform for Research, Testing and Validation of Technologies supporting a Sustainable Blue Economy (TEC4Sea)

Description: Specialised in the field of marine robotics, telecommunication and ocean environments, TEC4Sea gathers a set of laboratories, testbeds, equipment and support facilities for experimentation in controlled and real environments.

Keywords: Marine robotics tests, telecommunications, sensing technologies, ocean environments

Equipment: Test tanks; anechoic chamber; acoustic equipment for underwater signal processing; optical and image sensors; testing of wireless maritime networks; robotic platforms capable of supporting different payloads, including buoys and air, surface and underwater vehicles; 19m vessel for scientific research

Location: INESC TEC

Contact information: Paulo Mónica Oliveira - [email protected] - (+351) 22 834 055

Robotics and Autonomous Systems Laboratory

Description: Specialised in autonomous systems, robotic prototypes and underwater sensors, the Robotics and Autonomous Systems Laboratory has a variety of equipment and top facilities at two distinct locations (ISEP and FEUP), including a free indoor area for robot development and testing, a marine robotics test tank, two teaching labs and classrooms that support educational activities, additional research facilities, and an additional test tank where underwater systems are tested.

Keywords: Autonomous systems, robotics prototypes, tissue development, R&D activities, underwater sensors

Equipment: 2 test tanks, a large set of robotics platforms (underwater, surface, air and land), a large industrial 3D printer

Location: INESC TEC

Contact information: Eduardo Silva (ISEP) - [email protected] / Aníbal Matos (FEUP) - [email protected] - (+351) 22 834 0554

Smart Grids and Electrical Vehicles Laboratory (SGEVL)

Description: The SGEVL has expertise in electronic vehicles, smart grids, electric mobility, energy storage and renewable production, and offers several services for the industry, R&D activities, or community in general, in addition to consultancy services.

Keywords: Electric vehicles, smart grids, electric mobility, energy storage and renewable production

Equipment: Design and modelling of control systems, algorithms and electronics, general prototyping and power electronics and light mechanics, and performance and operation tests with electrical equipment and integrated/system tests

Location: INESC TEC

Contact information: Luís Miguel Miranda - [email protected] - (+351) 22 209 4000

Ultrafast Laser Spectroscopy for Biomedicine

Description: Specialised in Ultrafast and Vibrational Laser Spectroscopy.

Keywords: Spectroscopy, laser, vibrational, ultrafast

Equipment: Stimulated Raman Spectroscopy (SR) with highly increased acquisition speeds compatible with current clinical practices, low-cycle lasers (7 fs) with broad spectrum and high peak power for real-time and multimarker fluorescence lifetime imaging microscopy measurements

Location: U.Porto Faculty of Sciences (FCUP) / IFIMUP

Contact information: João Pedro Araújo - [email protected] - (+351) 22 040 2362

Animal Facility

Description: With expertise in the area of animal models, oncology, infection and neurology, this unit is dedicated to the production and maintenance of laboratory animals. The facility provides veterinary care and advice on laboratory animals, mainly rats and rabbits, and holds approximately 2,500 cages of laboratory rodents under SPF conditions. The aim of the facility is to support scientific projects associated with animal experimentation and to ensure high animal welfare standards throughout the development of such projects, encouraging the application of the 3Rs and high-quality animal research.

Keywords: Oncological, neurological, immunological diseases, production of genetically modified mice and zebrafish, biosafety level 2 and 3 infectious models, bio-imaging

Equipment: MicroCT, MicroUltrasound, X-Ray, ColoView, Ivis Lumina, Inverted microscope and microinjection set-up, operative conditioning chamber

Location: U.Porto Institute for Research and Innovation in Health (i3S)

Contact information: Sofia Lamas - [email protected] - (+351) 22 607 4979

Advanced Light Microscopy

Description: This unit specialises in imaging and cell biology, oncology and infection. It has extensive experience in a wide range of techniques, including transmission microscopy, widefield and laser scanning fluorescence confocal microscopy, TIRFM and digital image analysis. The unit also offers scientific advice on experiment design, training in equipment operation and in image analysis, and scientific consultancy in the development of research projects.

Keywords: Advanced light microscopy, nanoscopy, cells, tissues, small model organisms

Equipment: Confocal laser scanning microscopes, TCS SP5 & TCS SP8, Leica Microsystems; Rotating disk microscope, Revolution XD, Andor Technologies; Self-built light-sheet microscope, DLSFM; TIRF microscope

Location: U.Porto Institute for Research and Innovation in Health (i3S)

Contact information: Paula Sampaio - [email protected] - (+351) 22 607 4985

Animal Resources Unit

Description: Specialisation in the area of biomedical research, in particular animal models and preclinical evaluation.

Keywords: Biomedical research, laboratory animals, rodents, pigs, animal models

Equipment: Anaesthetic system, ATU IVC rack, ALLENTOWN, ATU-T2LM-12, Dump chamber, Biosafety exchange station, Decontaminator, Horizontal steriliser

Location: U.Porto Faculty of Medicine (FMUP)

Contact information: Patrícia Ribeiro - [email protected] - (+351) 22 042 6860

Biobank

Description: The ISPUP Biobank stores hundreds of thousands of biological samples from the Institute's population cohort participants. These samples, which include urine, plasma, serum and complete blood, contain information about the participants of ISPUP's longitudinal studies, namely their life circumstances, which allows for exhaustive characterisation of their health and well-being. The Biobank has made data sharing possible among international research groups, especially in the field of nutrition, environmental and perinatal health.

Keywords: Biomedical research; epidemiology; cohorts

Equipment: Cooling cabinets

Location: U.Porto Institute of Public Health (ISPUP)

Contact information: Mariana Mendes – [email protected] - (+351) 22 2061820


Biochemistry Laboratory

Description: This group specialises in oncology and its activities include applied and fundamental research. It covers several fields, such as Clinical Biochemistry, Haematology, Immunology and Molecular and Cellular Biology. The research team belongs to the UCIBIO/REQUIMTE research group called Drugs, Targets and Biomarkers (DTB), which was evaluated as excellent by FCT in 2019.

Keywords: biomarkers, hereditary anaemia, inflammation, bioactive dialysis membrane, cannabinoids and the endocannabinoid system

Equipment: UPLC/MS-MS, cell culture facilities, PCR

Location: U.Porto Faculty of Pharmacy (FFUP)

Contact information: Natércia Teixeira - [email protected] - (+351) 22 042 8560


Biomechanics

Description: Specialised in biomechanics and 3D printing, this unit is geared towards the prevention and treatment of pathologies, customised diagnosis and therapy, and improving the performance of athletes through personalised and adapted solutions, offering various services such as the development of devices/solutions for technical aids in the musculoskeletal area, development of devices to assess physical condition, optimisation of sports equipment, and more.

Keywords: Numerical simulation, biomechanics, occupational health and safety, medical image processing, 3D printing

Equipment: MVN-LINK, Xsens technologies B.V.; Quote No.ABT-01657-0-AnyBody Modeling System™, Abaqus, mimics, EEG and ECG systems, compression and uniaxial/ biaxial equipment, 3D printing; Equivital eq02+ LifeMonitor (Equivital EQ02, Hidalgo, UK); FARO laser scanner

Location: Institute of Science and Innovation in Mechanical and Industrial Engineering (INEGI)

Contact information: Nilza Ramião - [email protected] - (+351) 22 957 8710

Biomechanics Lab

Description: Specialisation in the field of sports biomechanics, namely in human movement analysis, strength assessment, muscle activity and pain, and training assessment.

Keywords: Gait analysis, running analysis, dual media, underwater motion capture, sports motion

Equipment: Land-based motion capture system (12 Oqus cameras, Qualisys, Sweden), water-based motion capture system (6 Oqus cameras, Qualisys, Sweden); 5 Bertec force platforms (Bertec Inc, USA); 1 Kistler force platform (Kistler, Switzerland); 1 instrumented treadmill with force platforms (AMTI, USA); Stabilometry system (Biodex Balance System, Biodex, USA); Delsys Trigno EMG (Delsys, USA); pressure insoles (Pedar-X, Novel, Germany); pressure pads (Tekscan, USA); pressure plate (emed, Novel, Germany)

Location: U.Porto Faculty of Sport (FADEUP) / LABIOMEP

Contact information: João Paulo Vilas-Boas - [email protected] - (+351) 96 902 1297

BoneLab

Description: Specialised in the field of cell culture and microscopy, the Bone Lab focuses its research mainly on bone metabolism and regeneration, covering in vitro, ex vivo and in vivo methodologies. The main objective is a deeper understanding of bone tissue functionality in physiological and pathological conditions. The Bone Lab has also established itself as a research institution in cytotoxicity and biocompatibility assessment of a diverse range of molecules, devices and materials.

Keywords: Biocompatibility, cytocompatibility, in vitro assays, ex vivo assays, cell culture

Equipment: Cell culture facilities, optical and fluorescent microscopy, live cell imaging, gene and protein expression assays; Bacterial culture facilities, fungal culture facilities, optical microscopy, fluorescent microscopy, gene and protein expression assays

Location: U.Porto Faculty of Dental Medicine (FMDUP)

Contact information: Maria Helena Fernandes - [email protected] - (+351) 22 090 1100

Cardiac Intervention Technologies Database

Description: Specialised in the field of cardiovascular sciences, namely cardiovascular disease and health technologies.

Keywords: Coronary heart disease, health technologies

Equipment: Database

Location: U.Porto Faculty of Medicine (FMUP) / CINTESIS

Contact information: Altamiro Costa Pereira - [email protected] - (+351) 22 551 3622


Cardiovascular Centre

Description: UnIC specialises in the field of cardiovascular science, molecular biology and clinical assessment, namely in coronary or valvular surgery, heart failure, skeletal and heart muscle, muscle physiology and physiopathology, and protein quantification, among others.

Keywords: Clinical research, cardiovascular sciences, coronary surgery, valvular surgery, cohorts

Equipment: Isolated Muscle System, 1500A, Aurora Scientific Inc.; Vibratome, 7000smz-2, Campden Instruments Ltd.; Biomimetic Myocardial Culture System, MyoDish System, InVitroSys GmgH; Vibratome, 7000smz-2, Campden Instruments Ltd.; CO2 Incubator, HERACELL 150i, ThermoScientific; Laminar flow cabinet class II, MSC-Advantage 1.2, ThermoScientific; ChemiDoc (Biorad) Image System; Thermal Cycler (Biorad); PikoReal 96 (Thermo Scientific) real-time PCR system; Odissey (LiCor) Infrared Imaging System

Location: U.Porto Faculty of Medicine (FMUP) / UnIC

Contact information: Adelino Leite-Moreira - [email protected] - (+351) 22 042 6820

Cohorts

Description: ISPUP focuses on biomedical research and epidemiology and manages the organisation of more than 10 research cohorts, including EPIteen, Generation XXI, Very Preterm babies and Men Who Have Sex With Men. These types of epidemiological studies are essential for public health research. The information obtained through cohort studies provides answers to several scientific questions. It is used for planning health promotion, health protection and disease prevention measures.

Keywords: Biomedical research, epidemiology, cohorts

Equipment: Databases

Location: U.Porto Institute of Public Health (ISPUP)

Contact information: Cátia Ferreira - [email protected] - (+351) 22 206 1820


DXA Body Composition, Nutrition & Health

Description: BODYCOMPNUT is specialised in body composition, nutrition and health.

Keywords: Biomedical research, body composition research, nutritional status, DXA, segmental and regional DXA

Equipment: DXA, Bone Densitometer Hologic Horizon WI, Hologic

Location: U.Porto Faculty of Nutrition and Food Science (FCNAUP)

Contact information: Teresa Amaral - [email protected] - (+351) 91 901 5762


Fermented Food Lab

Description: FERMFOODS is specialised in biochemical and food sciences.

Keywords: Food science research, fermented food, biochemical processes, high-performance liquid chromatography, innovation

Equipment: HPLC Agilent Technologies 1260 Infinity II, Multiskan™ FC microplate reader with incubator, incubating orbital shaker (Professional 3500), top loading VWR® VAPOUR-Line autoclaves

Location: U.Porto Faculty of Nutrition and Food Science (FCNAUP)

Contact information: Duarte Torres - [email protected] - (+351) 96 522 8602

Genomics

Description: This unit provides researchers with state-of-the-art technological solutions in the genomics field and in high-performance analysis. It specialises in fields such as genomics, oncology, infection and neurology, offering technical experience and support through experimental design, development of protocols and guidelines for data analysis.

Keywords: Next generation sequencing, microarrays, Sanger sequencing, real-time and digital PCR

Equipment: NextSeq550 Illumina, GeneTitan Affymetrix, S5XL Ion Torrent

Location: U.Porto Institute for Research and Innovation in Health (i3S)

Contact information: Ana Mafalda Rocha - [email protected] - (+351) 22 607 4983

Global Congestive Heart Failure Registry

Description: Specialisation in cardiovascular sciences and clinical assessment, namely heart failure, cardiovascular sciences in general, clinical research and epidemiology.

Keywords: Heart failure, cardiovascular sciences, clinical research, epidemiology

Equipment: Database

Location: U.Porto Faculty of Medicine (FMUP) / CINTESIS

Contact information: José Silva-Cardoso - [email protected] - (+351) 22 551 3622

Inflamatory Diseases Record and Software

Description: Specialisation in clinical assessment and inflammation, namely inflammatory bowel disease, Chron's disease, and gastroenterology, among others.

Keywords: Azathioprine, Crohn's disease, clinical research, gastroenterology, inflammatory bowel disease

Equipment: Database

Location: U.Porto Faculty of Medicine (FMUP) / CINTESIS

Contact information: Fernando Magro - [email protected] - (+351) 22 551 3622


Laboratory of Neuropsychophysiology

Description: The Neuropsychophysiology Laboratory, specialises in neuroscience, namely in cognitive neuroscience and carries out research in both Affective and Social Cognitive Neurosciences, focused on EEG/ERP methods and meta-analysis approaches. The lab provides equipment for high-density EGG recordings for adults and children, portable EGG, psychophysiological recordings (polygraphs) and eye tracking.

Keywords: Neuropsychology, social neuroscience, cognitive and affective neuroscience, human physiology, human neurophysiology

Equipment: High density and high impedance EEG/ERP System (128 channels) by EGI - Electrical Geodesics, Inc.

Location: U.Porto Faculty of Psychology and Education Science (FPCEUP)

Contact information: Fernando Barbosa - [email protected] - (+351) 22 040 0651


Microbiology Laboratory

Description: This group specialises in the field of infection. Its activities include applied and basic research and cover different Microbiology fields, such as Bacteriology, Mycology, Parasitology and Virology. It also carries out research in Applied Biotechnology and Cellular Biology.

Keywords: Microbiology, antibiotics, biocides and metal resistance, molecular and serological analysis, prevention and treatment of infectious diseases

Equipment: PCR and real-time PCR, cultivation rooms, cultivations rooms P1 and P2, flow cytometer, plate spectrophotometer, FTIR, PFGE

Location: U.Porto Faculty of Pharmacy (FFUP)

Contact information: Anabela Cordeiro - [email protected] - (+351) 22 042 8582


Mutant and Transgenic Animal Unit (UAMT)

Description: UAMT offers services focused on the production of mutant mice using CRISPR/Cas technology (knock-out, knock-in, transgenics), as well as homologous recombination (target gene) by injecting blastocysts with genetically manipulated ES cells, in the context of experimental projects approved by DGAV. UAMT also offers a portfolio of services such as the re-derivation of mutant and transgenic strains of mice.

Keywords: Biomedical research; animal models; genetic engineering; CRISPR/Cas; micromanipulation of embryos

Equipment: Automated micromanipulation system, AM6000, Leica.

Location: U.Porto Faculty of Medicine (FMUP)

Contact information: Miguel Soares - [email protected] - (+351) 22 042 6779

Obstetric Record

Description: Specialisation in obstetrics, namely in the electronic record of health data.

Keywords: Obstetrics; electronic health record; pregnancy; data protection.

Equipment: Database

Location: U.Porto Faculty of Medicine (FMUP) / CINTESIS

Contact information: Ricardo Cruz-Correia - [email protected] - (+351) 22 5513622


Pharmacology Laboratory

Description: This Laboratory specialises in pharmacology and drug development. It is integrated into courses such as histology, physiology, basic and clinical pharmacology, molecular neuroscience, therapeutics and pharmaceutical assistance to study a disease's molecular mechanisms and develop rational therapeutic approaches to human health.

Keywords: Pharmacology; new therapeutics

Equipment: HPLC-FL

Location: U.Porto Faculty of Pharmacy (FFUP)

Contact information: Jorge Gonçalves - [email protected] - (+351) 22 042 8626

Pharmaceutical Technology Laboratory

Description: The Organic and Pharmaceutical Chemistry Laboratory (LQOF), which specialises in chemistry, spectrometry, drug development and pharmacology, comprises two classroom laboratories, three research laboratories and three equipment rooms (MW, IR, UV, HPLC, GC-MS).

Keywords: Nanomedicine, controlled drug release, 3D printing

Equipment: HPLC-DAD, dissolution equipment

Location: U.Porto Faculty of Pharmacy (FFUP)

Contact information: Paulo Costa - [email protected] - (+351) 22 042 8620

Peptide and PNA Synthesis Service (POP-UP)

Description: POP-UP specialises in the fields of spectrometry and proteomics. It aims to provide the scientific and technological community (from academic institutions, businesses or other entities), particularly in northern Portugal, with services such as the synthesis, purification and analysis of peptides and PNAs. The latest equipment is made available for these services, as well as the experience and highly specialised knowledge of the working group.

Keywords: Peptides; PNA Synthesis Service; HPLC; mass spectrometry

Equipment: Symphony X 24-channel multiplex synthesizer; Peptide synthesis equipment assisted by Liberty 1 microwave; HPLC-DAD; HPLC; LC/MS Finnigan Surveyor LCQ DECA XP MAX system; Amino acid analysis system using the AccQ-Tag method; NanoDrop™ One

Location: U.Porto Faculty of Sciences (FCUP)

Contact information: Paula Gomes – [email protected] - (+351) 22 0402563


Proteomics

Description: This unit is specialised in proteomics, oncology, infection and neurology. It provides access to mass spectrometry analysis of protein samples from extracts, solutions and gel bands.

Keywords: Proteomics; mass spectrometry; quantification; characterisation of post-translational modifications

Equipment: NanoUHPLC; MS Q-Exactive

Location: U.Porto Institute for Research and Innovation in Health (i3S)

Contact information: Hugo Osório – [email protected] - (+351) 22 6074981

Quality indicators in primary healthcare

Description: Specialisation in the field of clinical assessment, namely quality indicators and primary health care.

Keywords: Quality indicators; primary healthcare

Equipment: Database

Location: U.Porto Faculty of Medicine (FMUP) / CINTESIS

Contact information: Alberto Freitas – [email protected] - (+351) 22 5513622

Severe Asthma Record – Portugal

Description: Specialisation in clinical assessment, namely the one regarding asthma and the electronic record of health data.

Keywords: Asthma; electronic health record; respiratory function; medication adherence; COPD

Equipment: Database

Location: U.Porto Faculty of Medicine (FMUP) / CINTESIS

Contact information: João Almeida Fonseca – [email protected] - (+351) 22 5513622

Screening in Life Sciences

Description: This unit specialises in screening, oncology, infection and neurology. It provides the internal and external scientific community, as well as the industry, with state-of-the-art instruments and skills to resolve challenging (biological) issues with high throughput (HT) and high content (HC) technologies. The platform facilitates access to genetic and compound screening libraries and has been establishing collaborations to receive and expand its own libraries. The information generated using HT/HC is very valuable for a more detailed understanding of complex diseases, including cancer, neurology, immunology and infectious diseases.

Keywords: High throughput screening, high content screening, drug screening, screening libraries, image acquisition, bioimage analysis

Equipment: OperaPhenixPlus (Perkin-Elmer); INCELL Analyzer (GE Healthcare); JANUS Liquid Handler (Perkin-Elmer)

Location: U.Porto Institute for Research and Innovation in Health (i3S)

Contact information: André Maia – [email protected] - (+351) 22 6074981

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Telemedicine Technologies for Heart Failure

Description: Specialisation in cardiovascular sciences and clinical assessment, namely heart failure, cardiovascular sciences in general, clinical and multidisciplinary research and non-invasive telemonitoring.

Keywords: Heart failure, cardiovascular sciences, clinical research, multidisciplinary research, non-invasive telemonitoring

Equipment: scales, dynamometer, computers

Location: U.Porto Faculty of Medicine (FMUP) / CINTESIS

Contact information: José Silva-Cardoso - [email protected] - (+351) 22 551 3622

Toxicology Laboratory

Description: This Laboratory specialises in Toxicology and provides services such as toxicological analysis, monitoring of the serum drug level, determination of blood alcohol level and drug abuse in biological material and other samples, quantification of copper and iron in liver biopsy, quantification of toxic compounds in human blood and urine samples, quantification of various metals in samples, etc.

Keywords: Toxicology

Equipment: HPLC-EC; GC-MS/MS

Location: U.Porto Faculty of Pharmacy (FFUP)

Contact information: Félix Carvalho - [email protected] - (+351) 22 042 8600

Applied Chemistry Laboratory

Description: Research activities are carried out in the Applied Chemistry Laboratory, with a specialisation in spectrometry, through the Biochemical, Environmental and Industrial Analysis Group (GABAI), which is part of the Chemistry and Technology Network (REQUIMTE – an Associated Laboratory of the Ministry for Science, Technology and Higher Education).

Keywords: Analytical chemistry, electrochemistry, biophysics, nanoparticles

Equipment: UPLC-MS/MS; microplate reader, electrochemical impedance spectroscope, 3D printer, cell culture systems

Contact information: Alberto Araújo – [email protected] - (+351) 22 0428666



Chemistry and Biochemistry Department - Lab&Services

Description: FCUP|DQB – Lab&Services, which is specialised in spectrometry and physical-chemical analysis, specifically aims to provide support to Course Units in the 1st and 2nd Study Cycles managed by the Chemistry and Biochemistry Department (DQB) and assist research activities carried out by Lecturers and Researchers in the department. It also provides research support and services to other FCUP Departments, Research Units that work in partnership with FCUP and external entities to FCUP, for example, other Academic Institutions, Research Institutions, Polytechnic Institutes, Technological Centres, State Laboratories and Companies. The services provided include thermal analysis, molecular and atomic spectroscopic techniques, chromatographic techniques, structural and morphological analysis or analysis of physical properties.

Keywords: Spectroscopic techniques, physical and structural properties, chromatographic techniques, thermal analysis

Equipment: AAS, ET AAS; FTIR, NIR; NMR, fluorometre, DLS, refractometre; HPLC, UHPLC; DSC; STA.

Contact information: Nuno Mateus– [email protected] - (+351) 22 0402434



Laboratory of Bromatology and Hydrology

Description: This group is specialised in spectrometry. Its main activities are carried out in the field of technology, research and analysis for the community in the context of food science. The fields covered include the implementation, validation and application of chemical, physical and biological methodologies, in order to assess food quality, authenticity and safety. Our research team values collaboration with the industry, as well as with other universities and research groups.

Keywords: Nutritional analysis, lipids, vitamins

Equipment: GC-MS/MS; UPLC-MS/MS

Contact information: José Fernandes – [email protected] - (+351) 22 0428639


Organic and Pharmaceutical Chemistry Laboratory

Description: The Organic and Pharmaceutical Chemistry Laboratory (LQOF), which is specialised in chemistry, spectrometry, drug development and pharmacology, comprises two classroom laboratories, three research laboratories and three equipment rooms (MW, IR, UV, HPLC, GC-MS).

Keywords: medicinal chemistry, organic synthesis, pharmaceutical analysis, environmental analysis, drug discovery and design

Equipment: HPLC-DAD; UPLC UV/VIS/FLD, FTIR; Biotek – Synergy HT microplate reader; HPLC Column Packing System; Microwave Synthesis Lab station; UV/Vis Spectrophotometre with a dual cell Peltier Thermostat table

Contact information: Paulo Costa – [email protected] - (+351) 22 0428620



Pharmacognosy Laboratory

Description: The Pharmacognosy Laboratory at the Faculty of Pharmacy develops educational and research activities in the field of natural products. It is specialised in chemistry, inflammation, drug development, neurodegenerative diseases, oncology and natural products. The group's main interests include chemistry of natural products and the biological and pharmacological potential of matrices and compounds of natural origin, especially chemical entities obtained from plants, marine organisms and insects.

Keywords: Natural products, phytochemical, phenolic compounds, alkaloids, drug discovery

Equipment: HPLC-DADHPLC-DAD-ESI-MSn; UHPLC-ESI-QTOF-MS; ELISA plate reader, fluorometre, CO2 incubators, confocal microscopes, laminar flow cabinets, thermal cyclers

Contact information: Paula Andrade – [email protected] - (+351) 22 0428654

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